- Sums of 1-parameter functions, such as convoluted exponentials in fast
- Optional global analysis of up to about 50 data sets with the same
decay constants (e.g., multi-wavelength sets);
- Optional robust correction for response function in fast fluorescence
decay using standards .
- Running on a wide variety of computers.
- fully automatic: no starting estimates needed for the number of
components or for their parameters;
- modified Gauss-Newton least squares, with intensive searches from many
starting points to find the global optimum;
- optional spline approximation of model functions [2,3] for faster
analyses (probably unnecessary with current computers).
- R.W. Wijnaendts van Resandt, R.H. Vogel & S.W. Provencher: Double beam
fluorescence spectrometer with subnanosecond resolution: Application to
aqueous tryptophan. Rev. Sci. Instr. 53, 1392
- R.H. Vogel: SplMod User's Manual (1988).
- S.W. Provencher & R.H. Vogel: Regularization techniques for inverse
problems in molecular biology in: Numerical Treatment of Inverse Problems
in Differential and Integral Equations, eds. P. Deuflhard & E. Hairer
(Birkhäuser, Boston, 1983), pp. 304-319.
Download by clicking on the 5 files below and saving them from your
You need a Fortran compiler, except that the following (gzip'd)
executable may work on
your Linux system:
Short guide for the installation and test run; read this first;
splmod-manual.pdf (3710 kB);
hd83.pdf (1237 kB)
(useful, but not necessary reading);
gzip) Fortran source code;
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Last modified: 27 May 2012