LCModel User's Manual
Download the latest version (November 2013) of the figures (29 pages) by clicking on the following:
-
figures.pdf
(1.0Mbyte).
Download the latest version (February 2021) of the manual (184 pages) by clicking on the following:
-
manual.pdf
(1.3Mbyte).
Print the two files, preferably in duplex mode (printing on both sides of a page). Bind the two separately, so that they can be read side-by-side.
The Manual is a detailed reference manual; most users only need to read a small fraction of it (as specified in Section 1.1).
A note on LCModel versions:
- You should consistently use the same version in one study.
- Users can update to the latest version (6.3-x) at no charge. (The
LCModel version number is in the third line of each output summary plot.)
- Version 5 should be replaced with Version 6.3, unless you need
consistency with previous Version 5 analyses. Version 6.3 is important for
poor-quality spectra and spectra with strong lipid signals.
- Versions 6.0 & 6.1 & 6.2 should be replaced with Version 6.3.
- Version 6.3-x is what you download. It is fully backward compatible with the input of all previous versions.
For Version 6.1 users - New features in Version 6.2 of possible interest:
- Small improvements in the algorithms mean that the results will
differ slightly.
- Analysis of spectra with mainly lipid (and water plus possibly choline), as in vertebra, breast and liver.
For Version 6.0 users - New features in Version 6.1 of possible interest:
- Small improvements in the algorithms mean that the results will
differ slightly.
- Analysis of muscle spectra, particularly for IMCL (Section
3.1).
- Bruker ParaVision-3 files (Section 7.3.1).
- Output file for import to spreadsheet programs (Section 11.4.4).
- In multi-voxel analyses: combining PostScript files into one file
(Section 11.4.5); skipping over bad voxels (Section 11.4.6).
- GE multi-channel (phased-array) P-files (Section 11.9.1).
- Simultaneously analyzing a spectrum left & right of the water signal (Section 11.11).
For Version 5 users - New features in Version 6.0 of possible interest:
- Estimation of lipid and macromolecule signals, especially for tumors
and lesions (Section 3.1).
- Interactive selection and analysis of rectangular subsets of MRSI
slices (Section 3.2).
- Bruker, Siemens syngo and Toshiba data with LCMgui (Section 3.7).
- Multi-User installations of LCMgui (Section 7.2.1).
- Archiving files using extensions in LCMgui (Section 7.3.3.3).
- LCMgui user profiles, e.g., for 1.5T & 3T data or Siemens & GE data
on the same user account (Section 7.3.7).
- Batch processing of multiple analyses with LCMgui (Section 7.4.3.1).
- Selecting a subset of GE LX (and higher) frames, e.g., to eliminate
bad frames due to patient motion (Section 7.4.5.1).
- Filename filters in the LCMgui File Selector (Section 7.5.1.3).
- More convenient handling of off-resonance spectra (Section 11.3.1).
- Simulating your own basis spectra (Section 11.7).
- Imposing "soft constraints" on concentration ratios (Section 11.8).
- Coherent averaging of spectra (e.g., from phased arrays) (Section
11.9).
- Going back toward the old Version 5, e.g., for improved (but not perfect) consistency in large longitudinal studies (Section 11.17).
Contact: Stephen Provencher: sp@lcmodel.CA
Last modified: 16 February 2021