Sample LCModel Applications

Some Applications of LCModel (to 2005)

Discrimination of white matter lesions and multiple sclerosis plaques by short echo quantitative H-1 - magnetic resonance spectroscopy
Kapeller, P; Ropele, S; Enzinger, C; Lahousen, T; Strasser-Fuchs, S; Schmidt, R; Fazekas, F
J Neurology 10, 1229-1234 (2005).

Automatic repositioning of single voxels in longitudinal H-1 MRS studies
Hancu, I; Blezek, DJ; Dumoulin, MC
NMR Biomed 18, 352-361 (2005).

Methodology of H-1 NMR spectroscopy of the human brain at very high magnetic fields
Tkac, I; Gruetter, R
Appl Magn Reson 29, 139-157 (2005).

Quantitative proton MRS of Pelizaeus-Merzbacher disease - Evidence of dys- and hypomyelination
Hanefeld, FA; Brockmann, K; Pouwels, PJW; Wilken, B; Frahm, J; Dechent, P
Neurology 65, 701-706 (2005).

Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis
Sastre-Garriga, J; Ingle, GT; Chard, DT; Ramio-Torrenta, L; McLean, MA; Miller, DH; Thompson, AJ
Arch Neurology 62, 569-573 (2005).

Two-dimensional, J-resolved spectroscopic imaging of GABA at 4 Tesla in the human brain
Jensen, JE; Frederick, BD; Wang, LQ; Brown, J; Renshaw, PF
Magn Reson Med 54, 783-788 (2005).

Interindividual reproducibility of glutamate quantification using 1.5-T proton magnetic resonance spectroscopy
Jang, DP; Lee, JM; Lee, E; Park, S; Kim, JJ; Namkoong, K; Yoon, KJ; Kim, IY; Kim, SI
Magn Reson Med 53, 708-712 (2005).

Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span
von Kienlin, M; Kunnecke, B; Metzger, F; Steiner, G; Richards, JG; Ozmen, L; Jacobsen, H; Loetscher, H
Neurobiology of Disease 18, 32-39 (2005).

Hippocampal myo-inositol and cognitive ability in adults with Down syndrome - An in vivo proton magnetic resonance spectroscopy study
Beacher, F; Simmons, A; Daly, E; Prasher, V; Adams, C; Margallo-Lana, ML; Morris, R; Lovestone, S; Murphy, K; Murphy, DGM
Arch Gen Psychiatry 62, 1360-1365 (2005).

Increased prefrontal and hippocampal glutamate concentration in schizophrenia: Evidence from a magnetic resonance spectroscopy study
van Elst, LT; Valerius, G; Buchert, M; Thiel, T; Rusch, N; Bubl, E; Hennig, J; Ebert, D; Olbrich, HM
Biol Psychiatry 58, 724-730 (2005).

Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy
Marjanska, M; Curran, GL; Wengenack, TM; Henry, PG; Bliss, RL; Poduslo, JF; Jack, CR; Ugurbil, K; Garwood, M
Proc Natl Acad Sci USA 102, 11906-11910 (2005).

Grey and white matter GABA level differences in the human brain using two-dimensional, J-resolved spectroscopic imaging
Jensen, JE; Frederick, BD; Renshaw, PF
NMR Biomed 18, 570-576 (2005).

Growth restriction and the cerebral metabolic response to acute hypoxia of chick embryos in-ovo: A proton magnetic resonance spectroscopy study
Dixon, JC; Cady, EB; Priest, AN; Thornton, JS; Peebles, DM
Developmental Brain Res 160, 203-210 (2005).

Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients
Caetano, SC; Fonseca, M; Olvera, RL; Nicoletti, M; Hatch, JP; Stanley, JA; Hunter, K; Lafer, B; Pliszka, SR; Soares, JC
Neurosci Lett 384, 321-326 (2005).

Examining SLV-323, a novel NK1 receptor antagonist, in a chronic psychosocial stress model for depression
Czeh, B; Pudovkina, O; van der Hart, MGC; Simon, M; Heilbronner, U; Michaelis, T; Watanabe, T; Frahm, J; Fuchs, E
Psychopharmacology 180, 548-557 (2005).

Decreased prefrontal Myo-inositol in major depressive disorder
Coupland, NJ; Ogilvie, CJ; Hegadoren, KM; Seres, P; Hanstock, CC; Allen, PS
Biol Psychiatry 57, 1526-1534 (2005).

H-1 MR spectroscopic characteristics of kernicterus: A possible metabolic signature
Oakden, WK; Moore, AM; Blaser, S; Noseworthy, MD
Amer J Neuroradiology 26, 1571-1574 (2005).

In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus
Raman, L; Tkac, I; Ennis, K; Georgieff, MK; Gruetter, R; Rao, R
Developmental Brain Res 156, 202-209 (2005).

Statistical evaluation of time-dependent metabolite concentrations: estimation of post-mortem intervals based on in situ H-1-MRS the brain
Scheurer, E; Ith, M; Dietrich, D; Kreis, R; Husler, J; Dirnhofer, R; Boesch, C
NMR Biomed 18, 163-172 (2005).

Short TE single-voxel H-1-MR spectroscopy of hippocampal structures in healthy adults at 1.5 Tesla - how reproducible are the results?
Hammen, T; Stadlbauer, A; Tomandl, B; Ganslandt, O; Pauli, E; Huk, W; Neundorfer, B; Stefan, H
NMR Biomed 18, 195-201 (2005).

Magnetic resonance spectroscopy in patients with MELAS
Moller, HE; Kurlemann, G; Putzler, M; Wiedermann, D; Hilbich, T; Fiedler, B
J Neurological Sci 229, 131-139 (2005).

Anterior cingulate neurochemistry in social anxiety disorder: H-1-MRS at 4 Tesla
Phan, KL; Fitzgerald, DA; Cortese, BM; Seraji-Bozorgzad, N; Tancer, ME; Moore, GJ
Neuroreport 16, 183-186 (2005).

H-1-MRS alterations in the cerebellum of patients with familial hemilegic migraine type 1
Dichgans, M; Herzog, J; Freilinger, T; Wilke, M; Auer, DP
Neurology 64, 608-613 (2005).

High-field localized H-1 NMR spectroscopy in the anesthetized and in the awake monkey
Pfeuffer, J; Juchem, C; Merkle, H; Nauerth, A; Logothetis, NK
Magn Reson Imaging 22, 1361-1372 (2004).

Region and volume dependencies in spectral line width assessed by H-1 2D MR chemical shift imaging in the monkey brain at 7 T
Juchem, C; Merkle, H; Schick, F; Logothetis, NK; Pfeuffer, J
Magn Reson Imaging 22, 1373-1383 (2004).

Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients
Oz, G; Tkac, I; Charnas, LR; Choi, IY; Bjoraker, KJ; Shapiro, EG; Gruetter, R
Neurology 64, 434-441 (2005).

MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter
Vrenken, H; Barkhof, F; Uitdehaag, BMJ; Castelijns, JA; Polman, CH; Pouwels, PJW
Magn Reson Med 53, 256-266 (2005).

Mapping of temporal and parietal cortex in progressive nonfluent aphasia and Alzheimer's disease using chemical shift imaging, voxel-based morphometry and positron emission tomography
Zahn, R; Buechert, M; Overmans, J; Talazko, J; Specht, K; Ko, CW; Thiel, T; Kaufmann, R; Dykierek, P; Juengling, F; Hull, M
Psychiatry Res Neuroimaging 140, 115-131 (2005).

Proton magnetic resonance spectroscopy and magnetoencephalographic estimation of delta dipole density: A combination of techniques that may contribute to the diagnosis of Alzheimer's disease
Fernandez, A; Garcia-Segura, JM; Ortiz, T; Montoya, J; Maestu, F; Gil-Gregorio, P; Campo, P; Viano, J
Dementia Geriatric Cognitive Disorders 20, 169-177 (2005).

Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors
Schweinsburg, BC; Taylor, MJ; Alhassoon, OM; Gonzalez, R; Brown, GG; Ellis, RJ; Letendre, S; Videen, JS; McCutchan, JA; Patterson, TL; Grant, I HNRC Grp
J Neurovirology 11, 356-364 (2005).

Untreated pediatric primitive neuroectodermal tumor in vivo: Quantitation of taurine with MR spectroscopy
Kovanlikaya, A; Panigrahy, A; Krieger, MD; Gonzalez-Gomez, I; Ghugre, N; McComb, JG; Gilles, FH; Nelson, MD; Bluml, S
Radiology 236, 1020-1025 (2005).

Serial proton spectroscopy in a case of adult-onset subacute sclerosing panencephalitis
Michael, N; Erfurth, A; Ludemann, P; Schuierer, G; Moller, HE
Psychiatry Res Neuroimaging 139, 269-273 (2005).

Sex differences in N-acetylaspartate correlates of general intelligence: An H-1-MRS study of normal human brain
Jung, RE; Haier, RJ; Yeo, RA; Rowland, LM; Petropoulos, H; Levine, AS; Sibbitt, WL; Brooks, WM
NeuroImage 26, 965-972 (2005).

Detection of subclinical and overt hepatic encephalopathy and treatment control after L-ornithine-L-aspartate medication by magnetic resonance spectroscopy (H-1-MRS)
Hass, HG; Nagele, T; Seeger, U; Hosl, F; Gregor, M; Kaiser, S
Z Gastroenterologie 43, 373-378 (2005).

Late proton MR spectroscopy in children after traumatic brain injury: Correlation with cognitive outcomes
Hunter, JV; Thornton, RJ; Wang, ZJ; Levin, HS; Roberson, G; Brooks, WM; Swank, PR
Amer J Neuroradiology 26, 482-488 (2005).

A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania
Frey, BN; Folgierini, M; Nicoletti, M; Machado-Vieira, R; Stanley, JA; Soares, JC; Kapczinski, F
Human Psychopharmacology Clin Exper 20, 133-139 (2005).

Brain glutamine by MRS in a patient with urea cycle disorder and coma
Kojic, J; Robertson, PL; Quint, DJ; Martin, DM; Pang, YX; Sundgren, PC
Pediatric Neurology 32, 143-146 (2005).

Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study
Ohrmann, P; Siegmund, A; Suslow, T; Spitzberg, K; Kersting, A; Arolt, V; Heindel, W; Pfleiderer, B
Schizophrenia Res 73, 153-157 (2005).

Quantitative single-voxel spectroscopy: The reciprocity principle for receive-only head coils
Jost, G; Harting, I; Heiland, S
J Magn Reson Imaging 21, 66-71 (2005).

Proton magnetic resonance spectroscopic imaging in brain tumor diagnosis
Gruber, S; Stadlbauer, A; Mlynarik, V; Gatterbauer, B; Roessler, K; Moser, E
Neurosurgery Clinics N Amer 16, 101+ (2005).

Optimized diffusion-weighted spectroscopy for measuring brain glutamate apparent diffusion coefficient on a whole-body MR system
Valette, J; Guillermier, M; Besret, L; Boumezbeur, F; Hantraye, P; Lebon, V
NMR Biomed 18, 527-533 (2005).

Magnetization transfer effect on human brain metabolites and macromolecules
McLean, MA; Simister, RJ; Barker, GJ; Duncan, JS
Magn Reson Med 54, 1281-1285 (2005).

Incidence of brain creatine transporter deficiency in males with developmental delay referred for brain magnetic resonance imaging
Newmeyer, A; Cecil, KM; Schapiro, M; Clark, JF; Degrauw, TJ
J Devel Behav Pediatrics 26, 276-282 (2005).

H-1 magnetic resonance spectroscopy of autosomal ataxias
Viau, M; Marchand, L; Bard, C; Boulanger, Y
Brain Res 1049, 191-202 (2005).

MR relaxometry and 1H MR spectroscopy for the determination of iron and metabolite concentrations in PKAN patients
Hajek, M; Adamoviova, M; Herynek, V; Skoch, A; Jiru, F; Krepelova, A; Dezortova, M
Eur Radiology 15, 1060-1068 (2005).

Physiologic variability of single-voxel proton MR spectroscopic measurements at 3T
Wellard, RM; Briellmann, RS; Jennings, C; Jackson, GD
Amer J Neuroradiology 26, 585-590 (2005).

An automated algorithm for combining multivoxel MRS data acquired with phased-array coils
Maril, N; Lenkinski, RE
J Magn Reson Imaging 21, 317-322 (2005).

MRI and proton MR spectroscopy in acute disseminated encephalomyelitis
Mader, I; Wolff, M; Nagele, T; Niemann, G; Grodd, W; Kuker, W
Childs Nervous System 21, 566-572 (2005).

Elevated white matter myo-inositol in clinically isolated syndromes suggestive of multiple sclerosis
KTM Fernando, MA McLean, DT Chard, DG MacManus, CM Dalton, KA Miszkiel, RM Gordon, GT Plant, AJ Thompson, DH Miller
Brain 127, 1361-1369 (2004).

Highly resolved in vivo ¹H NMR spectroscopy of the mouse brain at 9.4 T
I Tkác, P-G Henry, P Andersen, CD Keene, WC Low, R Gruetter
Magn Reson Med 52, 478-484 (2004).

A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D ¹H proton spectroscopic imaging of the human brain
R Srinivasan, D Vigneron, N Sailasuta, R Hurd, S Nelson
Magn Reson Imaging 22, 523-528 (2004).

NMR measurement of brain oxidative metabolism in monkeys using ¹³C-labeled glucose without a ¹³C radiofrequency channel
F Boumezbeur, L Besret, J Valette, F Vaufrey, P-G Henry, V Slavov, E Giacomini, P Hantraye, G Bloch, V Lebon
Magn Reson Med 52, 33-40 (2004).

Quantitative ¹H-MRS of healthy human cortex, hippocampus, and thalamus: Metabolite concentrations, quantification precision, and reproducibility
JJG Geurts, F Barkhof, JA Castelijns, BMJ Uitdehaag, CH Polman, PJW Pouwels
J Magn Reson Imaging 20, 366-371 (2004).

Proton MRS in acute traumatic brain injury: Role for glutamate/glutamine and choline for outcome prediction
L Shutter, KA Tong, BA Holshouser
J Neurotrauma 21, 1693-1705 (2004).

3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia
P Tibbo, C Hanstock, A Valiakalayil, P Allen
Am J Psychiatry 161, 1116-1118 (2004).

Proton MR spectroscopy in succinic semialdehyde dehydrogenase deficiency
T Ethofer, U Seeger, U Klose, M Erb, B Kardatzki, E Kraft, GB Landwehrmeyer, W Grodd, A Storch
Neurology 62, 1016-1018 (2004).

Metabolic profile of the hippocampus of Zucker Diabetic Fatty rats assessed by in vivo ¹H magnetic resonance spectroscopy
M van der Graaf, SWJ Janssen, JJA van Asten, ARMM Hermus, CGJ Sweep, JA Pikkemaat, GJM Martens, A Heerschap
NMR Biomed 17, 405-410 (2004).

N-Acetylaspartate levels of left frontal cortex are associated with verbal intelligence in women but not in men: A proton magnetic resonance spectroscopy study
B Pfleiderer, P Ohrmann, T Suslow, M Wolgast, AL Gerlach, W Heindel, N Michael
Neuroscience 123, 1053-1058 (2004).

MR Imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: Analysis of 72 cases
JL Freeman, LT Coleman, RM Wellard, MJ Kean, JV Rosenfeld, GD Jackson, SF Berkovic, AS Harvey
Am J Neuroradiol 25, 450-462 (2004).

Brain metabolic alterations in medication-free patients with bipolar disorder
SR Dager, SD Friedman, A Parow, C Demopulos, AL Stoll, IK Lyoo, DL Dunner, PF Renshaw
Arch Gen Psychiatry 61, 450-458 (2004).

Differentiation of metastases from high-grade gliomas using short echo time ¹H spectroscopy
KS Opstad, MM Murphy, PR Wilkins, BA Bell, JR Griffiths, FA Howe
J Magn Reson Imaging 20, 187-192 (2004).

Guanidinoacetate methyltransferase deficiency: Differences of creatine uptake in human brain and muscle
R Ensenauer, T Thiel, KO Schwab, U Tacke, S Stöckler-Ipsiroglu, A Schulze, J Hennig, W Lehnert
Mol Genet Metab 82, 208-213 (2004).

Quantitation of simulated short echo time ¹H human brain spectra by LCModel and AMARES
M Kanowski, J Kaufmann, J Braun, J Bernarding, C Tempelmann
Magn Reson Med 51, 904-912 (2004).

MR imaging and spectroscopy in juvenile Huntington disease
M Schapiro, KM Cecil, J Doescher, AM Kiefer, BV Jones
Pediatr Radiol 34, 640-643 (2004).

Cerebral creatine kinase deficiency influences metabolite levels and morphology in the mouse brain: A quantitative in vivo ¹H and ³¹P magnetic resonance study
HJA in 't Zandt, WKJ Renema, F Streijger, C Jost, DWJ Klomp, F Oerlemans, CEEM Van der Zee, B Wieringa, A Heerschap
J Neurochem 90, 1321-1330 (2004).

Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury
S Ashwal, B Holshouser, K Tong, T Serna, R Osterdock, M Gross, D Kido
J Neurotrauma 21, 1539-1552 (2004).

In vivo ¹H magnetic resonance spectroscopy of rat brain after valproate administration
J Leib, J Braun, A Schilling, C Klingner, S Seyfert, W Vollmann, E Gedat, J Bernarding
Neuroradiology 46, 363-367 (2004).

Longitudinal study of MRS metabolites in Rasmussen encephalitis
RM Wellard, RS Briellmann, JC Wilson, RM Kalnins, DP Anderson, P Federico, GCA Fabinyi, IE Scheffer, AS Harvey, GD Jackson
Brain 127, 1302-1312 (2004).

Hepatitis C virus infection is associated with reduced white matter N-acetylaspartate in abstinent methamphetamine users
MJ Taylor, SL Letendre, BC Schweinsburg, OM Alhassoon, GG Brown, A Gongvatana, I Grant
J Internat Neuropsychol Soc 10, 110-113 (2004).

Discrimination between neurochemical and macromolecular signals in human frontal lobes using short echo time proton magnetic resonance spectroscopy
MA McLean, RJ Simister, GJ Barker, JS Duncan
Faraday Discuss 126, 93-102 (2004).

MR imaging and proton MR spectroscopic studies in Sjögren-Larsson syndrome: Characterization of the leukoencephalopathy
MAAP Willemsen, M van der Graaf, MS van der Knaap, A Heerschap, PHMF van Domburg, FJM Gabreëls, JJ Rotteveel
Am J Neuroradiol 25, 649-657 (2004).

Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder
SD Friedman, SR Dager, A Parow, F Hirashima, C Demopulos, AL Stoll, IK Lyoo, DL Dunner, PF Renshaw
Biol Psychiatry 56, 340-348 (2004).

Altered neurometabolite development in HIV-infected children. Correlation with neuropsychological tests
MA Keller, TN Venkatraman, A Thomas, A Deveikis, C LoPresti, J Hayes, N. Berman, I Walot, S Padilla, J Johnston-Jones, T Ernst, L Chang
Neurology 62, 1810-1817 (2004).

Severe hypomyelination associated with increased levels of N-acetylaspartylglutamate in CSF
NI Wolf, MAAP Willemsen, UF Engelke, MS van der Knaap, PJW Pouwels, I Harting, J Zschocke, EA Sistermans, D Rating, RA Wevers
Neurology 62, 1503-1508 (2004).

In vivo ¹³C NMR measurement of activity-dependent malate-aspartate shuttle flux in the brain
P-G Henry, K Ugurbil, R Gruetter
Proc ISMRM 11, 27 (2004).

Neurochemical profile of the hibernating ground squirrel measured by ¹H NMR spectroscopy
P-G Henry, KP Russeth, I Tkac, LR Drewes, MT Andrews, R Gruetter
Proc ISMRM 11, 30 (2004).

In vivo CSI of glutamate in the monkey brain
C Juchem, H Merkle, NG Logothetis, J Pfeuffer
Proc ISMRM 11, 32 (2004).

Eicosapentanoic acid supplementation alters ¹H MRS metabolite profiles in first episode psychosis
R Wellard, SJ Wood, M McConchie, GD Jackson, D Velakoulis, PD McGorry, C Pantelis, GE Berger
Proc ISMRM 11, 106 (2004).

Subclinical hepatic encephalopathy in children studied by in vivo ¹H NMR spectroscopy at 4 Tesla
I Tkac, HR Hamernick, S Weisdorf-Schindle, G Oz, P-G Henry, R Gruetter
Proc ISMRM 11, 107 (2004).

Proton MR spectroscopy of substantia nigra in the human brain at 4 Tesla: Measurement of high GABA concentrations
G Oz, PJ Tuite, M Terpstra, I Tkac, P Aia, J Lowary, R Gruetter
Proc ISMRM 11, 110 (2004).

Measurement of glutamate ADC in the monkey brain using an optimized diffusion-weighted STEAM sequence at 3T
J Valette, L Besret, F Boumezbeur, P Hantraye, G Bloch, V Lebon
Proc ISMRM 11, 258 (2004).

¹H-MRS detects brain metabolite changes associated with early onset type-1 diabetes
RM Wellard, D Rankins, G Jackson, G Werther, E Northam
Proc ISMRM 11, 292 (2004).

Quantitative 2-D proton spectroscopic imaging in children following traumatic brain injury
RJ Thornton, ZJ Wang, HS Levin, WM Brooks, PR Swank, JV Hunter
Proc ISMRM 11, 294 (2004).

Short TE proton MRS in acute and treated Graves' disease
ER Danielsen, T Elberling, AK Rasmussen, G Waldemar, U Feldt-Rasmussen, C Thomsen
Proc ISMRM 11, 298 (2004).

Measurement of brain oxidative metabolism in monkeys using ¹H-NMR spectroscopy without ¹³C editing and decoupling
F Boumezbeur, L Besret, J Valette, F Vaufrey, P-G Henry, V Slavov, E Giacomini, P Hantraye, G Bloch, V Lebon
Proc ISMRM 11, 300 (2004).

Unearthing tiny signals in ¹H NMR spectra from the human brain: Measurement of Vitamin C and phosphomono and diesters in vivo
M Terpstra, P-G Henry, R Gruetter
Proc ISMRM 11, 309 (2004).

MRS shows glial increase but no neuro-axonal damage in MS NAWM
H Vrenken, F Barkhof, J Castelijns, C Polman, P Pouwels
Proc ISMRM 11, 466 (2004).

Evidence of elevated glutamate and glial activity in multiple sclerosis using TE-averaged spectroscopy at 3T
R Srinivasan, N Sailasuta, R Hurd, S Nelson, D Pelletier
Proc ISMRM 11, 467 (2004).

Prefrontal N-acetylaspartate:creatine ratio predicts functional outcome eighteen months after a first psychotic episode
SJ Wood, G Berger, D Velakoulis, P Conus, GW Stuart, M Lambert, PD McGorry, P Desmond, C Pantelis
Proc ISMRM 11, 522 (2004).

TE averaged PRESS: A better tool for diagnosing early Alzheimer's disease?
I Hancu, E Zimmerman, T O'Keefe, N Sailasuta, R Hurd
Proc ISMRM 11, 527 (2004).

Automated classification of ¹H MRS brain tumor spectra: A linear discriminant analysis comparison of LCModel quantification versus complete spectra
KS Opstad, C Ladroue, JR Griffiths, FA Howe
Proc ISMRM 11, 609 (2004).

Quantitative 1H MRS and diffusion MRI of untreated pediatric primitive neuroectodermal tumors
NR Ghugre, A Panigrahy, A Kovanlikaya, I Gonzales, M Krieger, MD Nelson, S Bluml
Proc ISMRM 11, 614 (2004).

Correlation between T2-relaxometry and proton MRS abnormalities in different epilepsy syndromes
RS Briellmann, RM Wellard, GS Pell, AB Waites, GD Jackson
Proc ISMRM 11, 1330 (2004).

In vivo MR assessment of hippocampal volume and neurochemical changes in rats with altered corticosteroid milieu
MI Schubert, R Kalisch, I Sotiropoulos, C Catania, OF Almeida, N Sousa, DP Auer
Proc ISMRM 11, 1445 (2004).

Proton MR spectroscopic characterization of Alzheimer's disease, fronto-temporal type of dementia and progressive supranuclear palsy by a 3.0 Tesla system
M Mihara, N Hattori, K Abe, M Umeda, N Inoue, Y Someya, M Matsui, S Sakoda, T Sawada
Proc ISMRM 11, 1478 (2004).

Niacin insensitivity is related to ¹H MRS abnormalities in drug-naive first episode psychosis
SJ Wood, G Berger, M McConchie, RM Wellard, D Velakoulis, PD McGorry, G Jackson, C Pantelis
Proc ISMRM 11, 1484 (2004).

Comparison of glutathione (GSH) concentrations quantified with STEAM versus edited spectroscopy: Application to schizophrenia
M Terpstra, SC Schulz, JT Vaughan, K Ugurbil, KO Lim, R Gruetter
Proc ISMRM 11, 1485 (2004).

Metabolite T₁ relaxation is preserved in large multiple sclerosis lesions
C Laule, EE Brief, IM Vavasour, AL Traboulsee, DK Li, AL MacKay
Proc ISMRM 11, 1507 (2004).

Interrelation between MR based surrogate markers of multiple sclerosis, disease severity and altered neuroendocrinological functioning
EM Schumann, T Kümpfel, T Schirmer, M Blazevic, J Behrends, A Wismüller, C Trenkwalder, DP Auer
Proc ISMRM 11, 1509 (2004).

Brain creatine deficiency treatment: Long term brain 1H and 31P MRS monitoring study under different creatine regimen
M Bianchi, M Tosetti, V Leuzzi, R Battini, M Alessandri, G Cioni
Proc ISMRM 11, 1619 (2004).

Proton spectra in aged rats: Correlation with learning abilities
D Jirak, K Namestkova, M Burian, I Vorisek, E Sykova, M Hajek
Proc ISMRM 11, 2038 (2004).

Improved preoperative diagnostics of brain tumors by quantification of 1H-MRSI metabolites
A Stadlbauer, O Ganslandt, S Gruber, C Nimsky, R Buslei, R Fahlbusch, E Moser
Proc ISMRM 11, 2053 (2004).

An LCModel-based automatic software tool for the reconstruction of anatomically- and pathologically-matched voxels using high-resolution 3D-spectroscopic imaging: Applications in tumour patients
S Gruber, A Stadlbauer, V Mlynarik, O Ganslandt, E Moser
Proc ISMRM 11, 2078 (2004).

Glutamate/glutamine complex, myoinositol and lipid in late radiation-induced injury of the brain: An in vivo 1H MRS study
Y Chan, D Yeung, S Leung, F Lee
Proc ISMRM 11, 2079 (2004).

An automated algorithm for combining multivoxel MRS data acquired with multicoils
N Maril, RE Lenkinski
Proc ISMRM 11, 2136 (2004).

An approach for absolute quantification of single voxel MR spectroscopy with receive-only head coils
G Jost, I Harting, S Heiland
Proc ISMRM 11, 2257 (2004).

Simple absolute signal scaling for spectroscopic data acquired with phased-array coils at 1.5T
T Schirmer, S Kohler, D Gultekin, T Raidy
Proc ISMRM 11, 2259 (2004).

Evaluation of the effects of aging and gender differences on the concentrations of cerebral metabolites by general linear model analysis
N Hattori, M Mihara, K Abe, M Umeda, M Fukunaga, Y Someya, M Matsui, S Sakoda, T Sawada
Proc ISMRM 11, 2262 (2004).

Phosphocreatine and neurotransmitters changes in the newborn rat during acute hypoglycemia measured by in vivo ¹H NMR spectroscopy
I Tkac, R Rao, AT Basford, MK Georgieff, R Gruetter
Proc ISMRM 11, 2275 (2004).

The neurochemistry of cortical auditory processing: Insights from magnetic resonance spectroscopy and magnetoencephalography
P Sörös, N Michael, M Tollkötter, B Pfleiderer
Proc ISMRM 11, 2282 (2004).

Quantitative determination of postmortem intervals: in situ ¹H-MR spectroscopy of human brain compared to traditional forensic methods
E Scheurer, M Ith, K Yen, M Thali, P Vermathen, R Kreis, R Dirnhofer, C Boesch
Proc ISMRM 11, 2283 (2004).

Clues for the differentiation between autolytic and bacterial products in decomposing brain
M Ith, M Thali, E Scheurer, R Kreis, R Dirnhofer, C Boesch
Proc ISMRM 11, 2284 (2004).

A novel approach for reducing chemical shift registration error at 3T: Short TE CPRESS
N Sailasuta, RE Hurd, C Cunningham, D Vigneron, S Nelson J Pauly
Proc ISMRM 11, 2297 (2004).

Proton magnetic resonance spectroscopy (1H-MRS) of tibialis anterior muscle: Intra-individual variation of metabolite ratios in healthy volunteers
M Torriani, BJ Thomas, ME Jensen, EF Halpern, WE Palmer, DI Rosenthal
Proc ISMRM 11, 2400 (2004).

Functional proton magnetic resonance spectroscopy of the human primary visual cortex: Metabolite and neurotransmitter concentrations
R Katz-Brull, DC Alsop, RP Marquis, RE Lenkinski
Proc ISMRM 11, 2426 (2004).

Magnetization transfer spectroscopy of metabolites and macromolecules in human brain in vivo
MA McLean, RJ Simister, GJ Barker, JS Duncan
Proc ISMRM 11, 2428 (2004).

Improving sensitivity of MRS by motion-related error correction in patients with Huntington's disease
Y Kuznetsov, Y Boulanger
Proc ISMRM 11, 2446 (2004).

1H MRS study of acute lorazepam in healthy human brain
P Davanzo, J O'Neill, T Belin, T Oshiro, V Nikore, JR Alger, M Thomas
Proc ISMRM 11, 2447 (2004).

Propylene glycol is essential in the LCModel basis set for paediatric brain ¹H-MRS
W Oakden, MD Noseworthy
Proc ISMRM 11, 2456 (2004).

Acute leukoencephalopathy after inhalation of a single dose of heroin.
S Vella, R Kreis, KO Lovblad, M Steinlin
Neuropediatrics 34, 100-104 (2003).

Toward dynamic isotopomer analysis in rat brain in vivo: automatic quantitation of ¹³C NMR spectra using LCModel.
P-G Henry, G Öz, S Provencher, R Gruetter
NMR Biomed 16, 400-412 (2003).

Quantitative proton magnetic resonance spectroscopy of children with adrenoleukodystrophy before and after hematopoietic stem cell transplantation.
B Wilken, P Dechent, K Brockmann, J Finsterbusch, M Baumann, W Ebell, GC Korenke, PJW Pouwels, FA Hanefeld, J Frahm
Neuropediatrics 34, 237-246 (2003).

Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by ¹H-MRS at 3 Tesla.
S Gruber, R Frey, V Mlynárik, A Stadlbauer, A Heiden, S Kasper, GJ Kemp, E Moser
Invest Radiol 38, 403-408 (2003).

Measurement of reduced glutathione (GSH) in human brain using LCModel analysis of difference-edited spectra.
M Terpstra, P-G Henry, Rolf Gruetter
Magn Reson Med 50, 19-23 (2003).

Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.
S Herminghaus, L Frölich, C Gorriz, U Pilatus, T Dierks, H-J Wittsack, H Lanfermann, K Maurer, FE Zanella
Psychiatry Res: Neuroimaging 123, 183-190 (2003).

Developmental and regional changes in the neurochemical profile of the rat determined by in vivo ¹H NMR spectroscopy.
I Tkác, R Rao, MK Georgieff, R Gruetter
Magn Reson Med 50, 24-32 (2003).

Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients.
B Pfleiderer, N Michael, A Erfurth, P Ohrmann, U Hohmann, M Wolgast, M Fiebich, V Arolt, W Heindel
Psychiatry Res: Neuroimaging 122, 185-192 (2003).

Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
K Brockmann, P Dechent, B Wilken, O Rusch, J Frahm, F Hanefeld
Neurology 60, 819-825 (2003).

Hippocampal regional asymmetry assessed by ¹H-MRS in rolandic epilepsy.
S Lundberg, J Weis, O Eeg-Olofsson, R Raininko
Epilepsia 44, 205-210 (2003).

Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: a sham-controlled proton magnetic resonance spectroscopy (¹H MRS) study of healthy brain.
N Michael, M Gösling, M Reutemann, A Kersting, W Heindel, V Arolt, B Pfleiderer
Eur J Neurosci 17, 2462-2468 (2003).

Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
K Brockmann, P Dechent, M Meins, M Haupt, J Sperner, U Stephani, J Frahm, F Hanefeld
J Neurol 250, 300-306 (2003).

Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
R Rao, I Tkac, EL Townsend, R Gruetter, MK Georgieff
J Nutr 133, 3215-3221 (2003).

Neurotrophic effects of electroconvulsive therapy: A proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression.
N Michael, A Erfurth, P Ohrmann, V Arolt, W Heindel, B Pfleiderer
Neuropsychopharmacology 28, 720-725 (2003).

Metabolic changes in the vicinity of brain contusions: A proton magnetic resonance spectroscopy and histology study.
MU Schuhmann, D Stiller, M Skardelly, J Bernarding, PM Klinge, A Samii, M Samii, T Brinker
J Neurotrauma 20, 725-743 (2003).

Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression.
N Michael, A Erfurth, P Ohrmann, V Arolt, W Heindel, B Pfleiderer
Psychological Med 33, 1277-1284 (2003).

Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases.
U Seeger, U Klose, I Mader, W Grodd, T Nägele
Magn Reson Med 49, 19-28 (2003).

Magnetic resonance proton spectroscopy and diffusion weighted imaging of chick embryo brain in ovo.
DM Peebles, JC Dixon, JS Thornton, EB Cady, A Priest, SL Miller, CE Blanco, TL Mulder, RJ Ordidge, CH Rodeck
Developmental Brain Res 141, 101-107 (2003).

MR imaging and spectroscopy of a tuber cinereum harmartoma in a patient with growth hormone deficiency and hypogonadotropic hypogonadism.
DD Martin, U Seeger, MB Ranke, W Grodd
Am J Neuroradiol 24, 1177-1180 (2003).

Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex.
N Michael, A Erfurth, P Ohrmann, M Gössling, V Arolt, W Heindel, B Pfleiderer
Psychopharmacology 168, 344-346 (2003).

Characterization of oligodendrogliomas using short echo time ¹H MR spectroscopic imaging.
M Rijpkema, J Schuuring, Y van der Meulen, M van der Graaf, H Bernsen, R Boerman, A van der Kogel, A Heerschap
NMR Biomed 16, 12-18 (2003).

Myoinositol abnormalities in temporal lobe epilepsy.
RM Wellard, RS Briellmann, JW Prichard, A Syngeniotis, GD Jackson
Epilepsia 44, 815-821 (2003).

Reduced myo-inositol and total choline measured with cerebral MRS in acute thyrotoxic Graves' disease.
TV Elberling, ER Danielsen, ÅK Rasmussen, U Feldt-Rasmussen, G Waldemar, C Thomsen
Neurology 60, 142-145 (2003).

Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain.
D Liebetanz, S Fauser, T Michaelis, B Czéh, T Watanabe, W Paulus, J Frahm, E Fuchs
J Psychiatric Res 37, 277-286 (2003).

Detection of elevated glutathione in meningiomas by quantitative in vivo ¹H MRS.
KS Opstad, SW Provencher, BA Bell, JR Griffiths, FA Howe
Magn Reson Med 49, 632-637 (2003).

Regional brain chemical alterations in young children with autism spectrum disorder.
SD Friedman, DW Shaw, AA Artru, TL Richards, J Gardner, G Dawson, S Posse, SR Dager
Neurology 60, 100-107 (2003).

Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats.
S Vielhaber, AP Kudin, TA Kudina, D Stiller, H Scheich, A Schoenfeld, H Feistner, H-J Heinze, CE Elger, WS Kunz
Eur J Neurosci 18, 2292-2300 (2003).

A new leukoencephalopathy with brainstem and spinal cord involvement and high lactate.
MS van der Knaap, P van der Voorn, F Barkhof, R Van Coster, I Krägeloh-Mann, A Feigenbaum, S Blaser, JSH Vles, P Rieckmann, PJW Pouwels
Ann Neurol 53, 252-258 (2003).

Comparison of longitudinal metabolite relaxation times in different regions of human brain at 1.5 and 3 Tesla.
T Ethofer, I Mader, U Seeger, G Helms, M Erb, W Grodd, A Ludolph, U Klose
Magn Reson Med 50, 1296-1301 (2003).

Localized proton MRS of cerebral metabolite profiles in different mouse strains.
A Schwarcz, O Natt, T Watanabe, S Boretius, J Frahm, T Michaelis
Magn Reson Med 49, 822-827 (2003).

MR spectroscopy of muscle and brain in guanidinoacetate methyltransferase (GAMT)-deficient mice: Validation of an animal model to study creatine deficiency.
WKJ Renema, A Schmidt, JJA van Asten, F Oerlemans, K Ullrich, B Wieringa, D Isbrandt, A Heerschap
Magn Reson Med 50, 936-943 (2003).

Is myo-inositol a measure of glial swelling after stroke? A magnetic resonance study.
H Rumpel, WEH Lim, HM Chang, LL Chan, GL Ho, MC Wong, KP Tan
J Magn Reson Imaging 17, 11-19 (2003).

Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents.
P Davanzo, K Yue, MA Thomas, T Belin, J Mintz, TN Venkatraman, E Santoro, S Barnett, J McCracken
Am J Psychiatry 160, 1442-1452 (2003).

Lower levels of N-acetylaspartate in multiple sclerosis patients with the apolipoprotein E epsilon-4 allele.
C Enzinger, S Ropele, S Strasser-Fuchs, P Kapeller, H Schmidt, B Poltrum, R Schmidt, H-P Hartung, F Fazekas
Arch Neurol 60, 65-70 (2003).

Proton echo-planar spectroscopic imaging with highly effective outer volume suppression using combined presaturation and spatially selective echo dephasing.
A Chu, JR Alger, GJ Moore, S Posse
Magn Reson Med 49, 817-821 (2003).

¹H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
M Hájek, M Dezortová, R Liscák, J Vymazal, V Vladyka
Eur Radiol 13, 994-1000 (2003).

Magnetic resonance spectroscopy of cerebral cortex is normal in hereditary hyperekplexia due to mutations in the GLRA1 gene.
MAJ Tijssen, P Brown, D MacManus, MA McLean, C Davie
Mov Disord 18, 1538-1541 (2003).

Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
SJ Wood, G Berger, D Velakoulis, LJ Phillips, PD McGorry, AR Yung, P Desmond, C Pantelis
Schizophrenia Bull 29, 831-843 (2003).

Effects of alcoholism and gender on brain metabolism.
BC Schweinsburg, OM Alhassoon, MJ Taylor, R Gonzalez, JS Videen, GC Brown, TL Patterson, I Grant
Am J Psychiatry 160, 1180-1183 (2003).

T2-based segmentation of periventricular volumes for quantification of proton magnetic resonance spectra of multiple sclerosis lesions.
G Helms
MAGMA 16, 10-16 (2003).

Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report).
F Spaniel, T Hájek, J Tintera, P Harantová, M Dezortová, M Hájek
Acta Psychiatr Scand 107, 155-158 (2003).

Selective deficit of hippocampal N-acetylaspartate in antipsychotic-naive patients with schizophrenia.
D Fannon, A Simmons, L Tennakoon, S O'Céallaigh, A Sumich, V Doku, C Shew, T Sharma
Biol Psychiatry 54, 587-598 (2003).

Serial proton magnetic resonance spectroscopy of the brain in children undergoing cardiac surgery.
S Ashwal, BA Holshouser, MJ del Rio, KA Tong, RL Applegate, LL Bailey
Pediatr Neurol 29, 99-110 (2003).

Quantitative proton magnetic resonance spectroscopy of children with adrenoleukodystrophy before and after hematopoietic stem cell transplantation.
P Dechent, J Finsterbusch, B Wilken, K Brockmann, F Hanefeld, J Frahm
Proc ISMRM 11, 139 (2003).

Improvement of reproducibility by selection of MRS data depending on spectral quality expressed by lower bounds of linear model curve fitting.
H Kubo, M Harada, M Sakama, N Nishitani
Proc ISMRM 11, 148 (2003).

Striatal neurochemical changes in transgenic Huntington's disease mice detected by in vivo ¹H NMR spectroscopy.
I Tkac, CD Keene, PG Henry, WC Low, R Gruetter
Proc ISMRM 11, 192 (2003).

Dietary creatine supplementation in a mouse model of Huntington's disease.
RA Page, A Bainbridge, DA West, JS Thornton, HJ Parkes, EB Cady, GP Bates, B Woodman, RJ Ordidge, CA Davie
Proc ISMRM 11, 194 (2003).

Towards in vivo ¹³C isotopomer analysis in the rat brain.
PG Henry, I Tkac, R Gruetter
Proc ISMRM 11, 260 (2003).

Metabolic flux measurement from a 8 microliter volume in the rat brain using ex vivo ¹H-{¹³C} NMR spectroscopy combined with LCModel analysis.
J Valette, F Vaufrey, PG Henry, G Bonvento, F Boumezbeur, P Hantraye, G Bloch, V Lebon
Proc ISMRM 11, 262 (2003).

Anatomical and neurochemical changes in minimal hepatic encephalopathy and their neuropsychological correlates.
N Wyckoff, N Binesh, M Bugbee, K Yue, M Green, S Han, MA Thomas
Proc ISMRM 11, 279 (2003).

Neurochemical profile of childhood adrenoleukodystrophy by ¹H MRS at 4 Tesla.
G Oz, I Tkac, IY Choi, KJ Bjoraker, EG Shapiro, LR Charnas, R Gruetter
Proc ISMRM 11, 330 (2003).

Multinuclear MRS screening of untreated pediatric brain tumors.
S Bluml, MJ Albers, MD Krieger, FH Gilles, MD Nelson
Proc ISMRM 11, 337 (2003).

Anterior cingulate and amygdalar 1H MRS abnormalities in childhood autism.
J O'Neill, J Levitt, JT McCracken, AW Toga, JR Alger
Proc ISMRM 11, 338 (2003).

Comparison of metabolite T1 relaxation times in different brain regions at 1.5 and 3 Tesla.
T Ethofer, I Mader, U Seeger, A Ludolph, W Grodd, U Klose
Proc ISMRM 11, 434 (2003).

Age-related changes of cerebral metabolite concentrations: a quantitative proton MR spectroscopic study.
N Hattori, K Abe, M Umeda, M Fukunaga, N Inoue, Y Someya, M Matsui, S Sakoda, T Sawada
Proc ISMRM 11, 435 (2003).

Short TE proton spectroscopy in variant and familial Creutzfeldt Jakob disease.
R Cordery, D MacManus, J Collinge, M Rossor, A Waldman
Proc ISMRM 11, 438 (2003).

Absolute quantification of metabolic changes in the frontal brain of depressive patients before and after treatment: a proton MRS study at 3 T.
S Gruber, R Frey, A Stadlbauer, V Mlynarik, S Kasper, E Moser
Proc ISMRM 11, 440 (2003).

Statistical evaluation of 1H-MR spectra of the brain in situ for quantitative determination of postmortem intervals (PMI).
E Scheurer, M Ith, D Dietrich, R Kreis, J Huesler, R Dirnhofer, C Boesch
Proc ISMRM 11, 568 (2003).

Combination of ¹³C NMR spectroscopy with ¹⁸FDG detection reveals similar oxidative and glycolytic metabolism increases in the rat brain under physiological stimulation.
J Valette, G Bonvento, F Vaufrey, L Besret, PG Henry, F Pain, F Boumezbeur, P Hantraye, G Bloch, V Lebon
Proc ISMRM 11, 576 (2003).

SESAME: An interleaved multislice chemical shift imaging method with spatial presaturation and selective excitation.
R Katz-Brull, N Sailasuta, T Raidy, RE Lenkinski
Proc ISMRM 11, 1132 (2003).

Feasibility of highly resolved in vivo ¹H NMR spectroscopy of the mouse brain at 9.4 Tesla.
I Tkac, PG Henry, P Andersen, CD Keene, WC Low, R Gruetter
Proc ISMRM 11, 1148 (2003).

Quantitative mapping of Glx and myo-inositol in human brain by MR spectroscopic imaging at 3 Tesla.
Y Someya, N Hattori, M Umeda, M Fukunaga, N Inoue, M Matsui, T Sawada
Proc ISMRM 11, 1154 (2003).

Metabolite quantitation in the monkey brain by ¹H MRS using LCModel and MRI automatic segmentation.
F Boumezbeur, L Besret, R Maroy, F Vaufrey, P Hantraye, V Lebon, G Bloch
Proc ISMRM 11, 1156 (2003).

GUI for automatic post processing and display of 2D-SI data sets with LCModel.
C Ko, B Kreher, M Buechert
Proc ISMRM 11, 1157 (2003).

T2-based segmentation of periventricular volumes for quantification of MR spectra of multiple sclerosis lesions.
G Helms
Proc ISMRM 11, 1162 (2003).

LCModel analysis of spectra edited for glutathione (GSH).
M Terpstra, PG Henry, R Gruetter
Proc ISMRM 11, 1166 (2003).

Estimation of the cerebral metabolite concentrations in pure gray matter and white matter by in vivo proton MR spectroscopy.
N Hattori, K Abe, M Umeda, M Fukunaga, N Inoue, Y Someya, M Matsui, S Sakoda, T Sawada
Proc ISMRM 11, 1167 (2003).

Cerebral metabolite concentrations in pure gray and white matter calculated by proton MR spectroscopy and image segmentation.
U Seeger, T Nägele, I Mader, M Erb, T Ethofer, U Klose
Proc ISMRM 11, 1168 (2003).

Absolute quantification of brain metabolites in a mouse model of Huntington's disease.
A Bainbridge, RA Page, DA West, EB Cady, AN Priest, JS Thornton, GP Bates, B Woodman, RJ Ordidge, CA Davie
Proc ISMRM 11, 1954 (2003).

Proton magnetic resonance spectroscopy in an animal model of Parkinson's disease: effect of L-DOPA or Pramipexole treatment.
M Delfino, G Murer, C Trenkwalder, O Gershanik, D Auer
Proc ISMRM 11, 1956 (2003).

Quantitative proton MRS detects different cerebral metabolic responses of mouse strains to global ischemia.
O Natt, A Schwarcz, T Watanabe, S Boretius, J Frahm, T Michaelis
Proc ISMRM 11, 1960 (2003).

Evidence that GAD65 mediates a major fraction of GABA synthesis during seizures.
AB Patel, GM Chowdhury, RA de Graaf, DL Rothman, B Wang, KL Behar
Proc ISMRM 11, 1965 (2003).

Glucose and glial-neuronal metabolism in alpha-chloralose anesthetized rats measured by in vivo ¹³C NMR spectroscopy.
PG Henry, S Crawford, G Oz, K Ugurbil, R Gruetter
Proc ISMRM 11, 1967 (2003).

Proton MR spectroscopy at 7 Tesla in the macaque monkey.
J Pfeuffer, C Juchem, H Merkle, NK Logothetis
Proc ISMRM 11, 1971 (2003).

Is physiological motion important in MRS of the brain at 3T: Frame-to-frame PRESS acquisitions.
R Katz-Brull, RE Lenkinski
Proc ISMRM 11, 1990 (2003).

Quantitative proton MRS in Lhermitte-Duclos disease.
G Helms, D Greitz, O Flodmark
Proc ISMRM 11, 1995 (2003).

Quantitation of GABA in human brain using MEGA-PRESS editing and LCM analysis.
M Wylezinska, P Matthews, P Jezzard
Proc ISMRM 11, 1997 (2003).

Altered glutamate/glutamine levels within the left dorsolateral prefrontal cortex in acute mania - impact of tissue segmentation and related corrections.
B Pfleiderer, N Michael, M Gösling, V Arolt, W Heindel
Proc ISMRM 11, 2004 (2003).

Adolescents at high risk for schizophrenia studied by 1H MRS.
C Hanstock, P Allen, A Valiakalayil, L Paulson, P Tibbo
Proc ISMRM 11, 2009 (2003).

Medial temporal lobe changes in first episode psychosis measured by ¹H MRS at 3T.
RM Wellard, SJ Wood, GE Berger, PD McGorry, GD Jackson, C Pantelis
Proc ISMRM 11, 2011 (2003).

Fronto-temporal connectivity and violence in schizophrenia: A 1H-MRS study.
R Jones, A Simmons, N Tunstall, E Daly, M Isaac, D Murphy
Proc ISMRM 11, 2012 (2003).

Metabolite changes identified by serial proton magnetic resonance spectroscopy can differentiate long-term neurologic outcome in traumatic brain injury.
BA Holshouser, KA Tong, A Colohan, L Shutter
Proc ISMRM 11, 2032 (2003).

MRS and MRI insights into the diagnosis of the heredo-degenerative ataxias.
M Viau, C Arseneau, C Bard, S Fontaine, L Marchand, J Léveillé, Y Boulanger
Proc ISMRM 11, 2048 (2003).

Frontal lobe CSI abnormalities in obstructive sleep apnea.
RS Briellmann, F O'Donoghue, RM Wellard, T Waites, P Rochford, R Pierce, GD Jackson
Proc ISMRM 11, 2061 (2003).

Grey and white matter abnormalities in patients with chronic toxic encephalopathy: a preliminary study using DTI and 1H MR spectroscopy.
C Lavini, I Visser, MM De Win, CB Majoie, EM Wekking, L Reneman, G van der Laan, GJ den Heeten
Proc ISMRM 11, 2294 (2003).

Reproducibility of proton magnetic resonance spectroscopy in children.
FP MacMaster, N Carrey, M Given, S Sullivan, MH Schmidt
Proc ISMRM 11, 2522 (2003).

3-Nitropropionic acid increases cortical and hippocampal, but not striatal, taurine in the rat: Metabolic profiling with HR-MAS 1H-MRS.
TR Mitchell, MP Galloway, N Seraji-Bozorgzad, GJ Moore
Proc ISMRM 11, 2616 (2003).

Opposite effects of MDMA and SKF-38393 on striatal GABA: Neurochemical profile with HR-MAS 1H-MAS.
MP Galloway, TR Mitchell, N Seraji-Bozorgzad, DA Briston, J Chioini, ST Fricke, GJ Moore
Proc ISMRM 11, 2617 (2003).

Brain metabolism in vascular dementia and Alzheimer's disease assessed by quantitative in vivo proton MR spectroscopy.
U Pilatus, A du Mesnil de Rochemont, S Herminghaus, L Froelich, J Peters, T Kratzsch, K Maurer, H Lanfermann, FE Zanella
Proc ISMRM 11, 2623 (2003).

Diffusion tensor imaging in ALS compared with proton MR spectroscopy.
IK Mader, M Erb, M Gleichmann, JB Schulz, W Grodd, U Klose
Proc ISMRM 11, 2624 (2003).

Brain metabolite composition during early human brain development as measured by quantitative in vivo ¹H magnetic resonance spectroscopy.
R Kreis, L Hofmann, B Kuhlmann, C Boesch, E Bossi, PS Hüppi,
Magn Reson Med 48, 949-958 (2002).

Reproducibility of in vivo metabolite quantification with proton magnetic resonance spectroscopic imaging.
DT Chard, MA McLean, GJM Parker, DG MacManus, DH Miller,
J Magn Reson Imaging 15, 219-225 (2002).

Valproate-induced encephalopathy: Assessment with MR imaging and ¹H MR spectroscopy.
S Ziyeh, T Thiel, J Spreer, J Klisch, M Schumacher,
Epilepsia 43, 1101-1105 (2002).

Distinctly abnormal brain metabolism in late-onset ornithine transcarbamylase deficiency.
J Takanashi, A Kurihara, M Tomita, M Kanazawa, S Yamamoto, F Morita, H Ikehira, S Tanada, Y Kohno,
Neurology 59, 210-214 (2002).

Observation and identification of metabolites emerging during postmortem decomposition of brain tissue by means of in situ ¹H-magnetic resonance spectroscopy.
M Ith, P Bigler, E Scheurer, R Kreis, L Hofmann, R Dirnhofer, C Boesch,
Magn Reson Med 48, 915-920 (2002).

A short-echo-time proton magnetic resonance spectroscopic imaging study of temporal lobe epilepsy.
RJ Simister, FG Woermann, MA McLean, PA Bartlett, GJ Barker, JS Duncan,
Epilepsia 43, 1021-1031 (2002).

Brain N-acetylaspartate is elevated in Pelizaeus-Merzbacher disease with PLP1 duplication.
J Takanashi, K Inoue, M Tomita, A Kurihara, F Morita, H Ikehira, S Tanada, E Yoshitome, Y Kohno,
Neurology 58, 237-241 (2002).

Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis.
DT Chard, CM Griffin, MA McLean, P Kapeller, R Kapoor, AJ Thompson, DH Miller,
Brain 125, 2342-2352 (2002).

Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume.
MGC van der Hart, B Czéh, G de Biurrun, T Michaelis, T Watanabe, O Natt, J Frahm, E Fuchs,
Molecular Psychiatry 7, 933-941 (2002).

Proton MR spectroscopic study at 3 Tesla on glutamate/glutamine in Alzheimer's disease.
N Hattori, K Abe, S Sakoda, T Sawada,
Neuroreport 13, 183-186 (2002).

Reduced myo-inositol and total choline measured with cerebral MRS in acute thyrotoxic Graves' disease.
TV Elberling, ER Danielsen, ÅK Rasmussen, U Feldt-Rasmussen, G Waldemar, C Thomsen,
Neurology 60, 142-145 (2002).

Application of NMR spectroscopy to monitoring MELAS treatment: A case report.
HE Möller, D Wiedermann, G Kurlemann, T Hilbich, G Schuierer,
Muscle Nerve 25, 593-600 (2002).

Proton magnetic resonance spectroscopy of the thalamus in patients with chronic neuropathic pain after spinal cord injury.
PM Pattany, RP Yezierski, EG Widerström-Noga, BC Bowen, A Martinez-Arizala, BR Garcia, RM Quencer
Am J Neuroradiol 23, 901-905 (2002).

Proton MRS in Kennedy disease: Absolute metabolite and macromolecular concentrations.
I Mader, J Karitzky, U Klose, U Seeger, A Sperfeld, T Naegele, F Schick, A Ludolph, W Grodd,
J Magn Reson Imaging 16, 160-167 (2002).

Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy.
A Kumar, A Thomas, H Lavretsky, K Yue, A Huda, J Curran, T Venkatraman, L Estanol, J Mintz, M Mega, A Toga,
Am J Psychiatry 159, 630-636 (2002).

Increase in amino acids in the pons after sleep deprivation: A pilot study using proton magnetic resonance spectroscopy.
H Murck, T Struttmann, M Czisch, T Wetter, A Steiger, DP Auer,
Neuropsychobiology 45, 120-123 (2002).

Proton MR spectroscopy of neurometabolites in hepatic encephalopathy during L-ornithine-L-aspartate treatment - Results of a pilot study.
A Delcker, B Turowski, U Mihm, P Raab, O Rusch, U Pilatus, S Zeuzem, FE Zanella,
Metab Brain Dis 17, 103-111 (2002).

Proton magnetic resonance spectroscopy with metabolite nulling reveals regional differences of macromolecules in normal human brain.
I Mader, U Seeger, J Karitzky, M Erb, F Schick, U Klose,
J Magn Reson Imaging 16, 538-546 (2002).

Quantitative ¹H-magnetic resonance spectroscopy of human brain: Influence of composition and parameterization of the basis set in linear combination model-fitting.
L Hofmann, J Slotboom, B Jung, P Maloca, C Boesch, R Kreis,
Magn Reson Med 48, 440-453 (2002).

¹H MRS brain measures and acute lorazepam administration in healthy human subjects.
P Brambilla, JA Stanley, M Nicoletti, K Harenski, KF Wells, AG Mallinger, MS Keshavan, JC Soares,
Neuropsychopharmacology 26, 546-551 (2002).

In vivo GABA+ measurement at 1.5T using a PRESS-localized double quantum filter.
MA McLean, AL Busza, LL Wald, RJ Simister, GJ Barker, SR Williams,
Magn Reson Med 48, 233-241 (2002).

Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation.
JY Garbern, DA Yool, GJ Moore, IB Wilds, MW Faulk, M Klugmann, KA Nave, EA Sistermans, MS van der Knaap, TD Bird, ME Shy, JA Kamholz, IR Griffiths,
Brain 125, 551-561 (2002).

Effects of physiologic human brain motion on proton spectroscopy: Quantitative analysis and correction with cardiac gating.
PM Pattany, IH Khamis, BC Bowen, K Goodkin, RG Weaver, JB Murdoch, MJD Post, RM Quencer,
Am J Neuroradiol 23, 225-230 (2002).

New syndrome characterized by hypomyelination with atrophy of the basal ganglia and cerebellum.
MSvan der Knaap, S Naidu, PJW Pouwels, S Bonavita, R van Coster, L Lagae, J Sperner, R Surtees, R Schiffmann, J Valk,
Am J Neuroradiol 23, 1466-1474 (2002).

Thalamic neurodegeneration in multiple sclerosis.
A Cifelli, M Arridge, P Jezzard, MM Esiri, J Palace, PM Matthews,
Ann Neurol 52, 650-653 (2002).

Human brain: Biochemical lateralization in normal subjects.
R Jayasundar,
Neurol India 50, 267-271 (2002).

Frontal lobe myoinositol abnormalities in temporal lobe epilepsy.
RM Wellard, RS Briellmann, A Syngeniotis, GD Jackson,
Proc ISMRM 10, 418 (2002).

A comparison of metabolite concentrations in primary generalised epilepsy and partial epilepsy using short echo time 1H spectroscopy and a double quantum GABA filter.
RJ Simister, MA McLean, GJ Barker, JS Duncan,
Proc ISMRM 10, 420 (2002).

Influence of composition of the basis set in linear combination model fitting of ¹H-MR spectra of human brain.
L Hofmann, C Boesch, R Kreis,
Proc ISMRM 10, 527 (2002).

On the quantification of low concentration metabolites by ¹H NMR spectroscopy in human brain at 7 Tesla.
I Tkac, K Ugurbil, R Gruetter,
Proc ISMRM 10, 528 (2002).

Metabolite nulling improves reliability of LCModel analysis of short echo time spectroscopy.
MA McLean, RJ Simister, GJ Barker, JS Duncan,
Proc ISMRM 10, 529 (2002).

Automatic quantitation of in vivo ¹³C spectra using LCModel.
P-G Henry, I Tkac, R Gruetter,
Proc ISMRM 10, 530 (2002).

Identification of metabolites emerging during autolysis and bacterial heterolysis of decomposing brain tissue by ¹H-MRS in situ and in vitro.
M Ith, P Bigler, E Scheurer, R Kreis, L Hofmann, R Dirnhofer, C Boesch,
Proc ISMRM 10, 580 (2002).

Antidepressants prevent stress-induced reductions of cerebral metabolites.
T Michaelis, T Watanabe, O Natt, S Boretius, M van der Hart, B Czeh, G de Biurrun, E Fuchs, J Frahm,
Proc ISMRM 10, 584 (2002).

MDMA ("Ecstasy") increases striatal but not prefrontal GABA in rat brain: Studies with high-resolution magic angle spinning proton magnetic resonance spectroscopy (HR-MAS 1H-MRS).
MP Galloway, ST Fricke, T Mitchell, N Seraji-Bozorgzad, GJ Moore,
Proc ISMRM 10, 585 (2002).

Short TE proton MRS in Graves' disease.
ER Danielsen, T Elberling, G Waldemar, U Feldt-Rasmussen, C Thomsen,
Proc ISMRM 10, 697 (2002).

Brain glycogen: An endogenous, insulin-sensitive energy reservoir.
I-Y Choi, R Gruetter,
Proc ISMRM 10, 944 (2002).

Proton MRS of rat brain after chronic repetitive transcranial magnetic stimulation.
T Michaelis, D Liebetanz, T Watanabe, B Czeh, W Paulus, E Fuchs, J Frahm
Proc ISMRM 10, 951 (2002).

Ex vivo neurochemical kinetics in brain tissue specimens monitored via quantitative HR-MAS proton magnetic resonance spectroscopy at 11.7T.
ST Fricke, MP Galloway, N Seraji-Bozorgzad, TR Mitchell, S Posse, GJ Moore,
Proc ISMRM 10, 952 (2002).

Metabolite and diffusion changes in the rat brain after Leksell Gamma Knife irradiation.
V Herynek, M Burian, D Jirák, R Liscák, K Námestková, M Hájek, E Syková
Proc ISMRM 10, 959 (2002).

in vivo MR studies in transgenic mouse model of Huntington's disease.
RA Page, DA West, EB Cady, JS Thornton, GP Bates, B Woodman, AN Priest, RJ Ordidge, CA Davie
Proc ISMRM 10, 960 (2002).

Striatal oxidative metabolic failure in an improved rat model of Huntington's disease monitored via HR-MAS proton magnetic resonance spectroscopy at 11.7T.
TR Mitchell, MP Galloway, ST Fricke, N Seraji-Bozorgzad, C Zajac-Benitez, GJ Moore,
Proc ISMRM 10, 961 (2002).

¹H MRS in mild cognitive impairment (MCI) and Alzheimer's disease (AD); Comparison of 1.5T and 3T.
K Kantarci, RC Petersen, BF Boeve, DS Knopman, SD Edland, GE Smith, RJ Ivnik, EG Tangalos, CR Jack, Jr,
Proc ISMRM 10, 971 (2002).

Reproducibilty of magnetic resonance spectroscopy (MRS) measurements in schizophrenic patients.
P Mullins, LM Rowland, J Bustillo, WM Brooks,
Proc ISMRM 10, 973 (2002).

Regional metabolic effects of sleep deprivation in depressed patients assessed by proton magnetic resonance spectroscopy.
DP Auer, D Schmid, T Merl, H Murck, A Steiger,
Proc ISMRM 10, 977 (2002).

Absolute quantification of metabolic changes in the brain of depressive patients.
A Stadlbauer, S Gruber, R Frey, V Mlynárik, S Kasper, E Moser,
Proc ISMRM 10, 978 (2002).

Staging of progressive multifocal leukoencephalopathy lesions using proton MR spectroscopy at 3T.
R Katz-Brull, IJ Koralnik, MA McLean, RE Lenkinski,
Proc ISMRM 10, 981 (2002).

Proton MRS of childhood adrenoleukodystrophy at 4 Tesla.
G Öz, I Tkác, I-Y Choi, JT Vaughan, EG Shapiro, MC Gibbs, LR Charnas, R Gruetter,
Proc ISMRM 10, 982 (2002).

Proton magnetic resonance spectroscopy of the thalamus: Evaluation of patients with chronic neuropathic pain following spinal cord injury.
PM Pattany, BC Bowen, RP Yezierski, EG Widerström-Noga, A Martinez-Arizala, RM Quencer,
Proc ISMRM 10, 987 (2002).

Gender and age effects in human white matter on MR spectroscopy at 4 Tesla.
K Zhong, L Chang, D Carasig, L Zimmerman, T Ernst,
Proc ISMRM 10, 1005 (2002).

Ketogenic diet in intractable epilepsy: An ¹H-MRS follow-up study in children.
DP Auer, M Wilke, G Liebhaber, F Baumeister,
Proc ISMRM 10, 1032 (2002).

Influence of increased tissue water content in multiple sclerosis lesions on the metabolite concentrations as measured by proton MR spectroscopy.
L Stawiarz, H Link,
Proc ISMRM 10, 1203 (2002).

Morphologic and metabolic alterations in a APP/PS double-transgenic mouse model for Alzheimer's disease.
M von Kienlin, B Kuennecke, G Higgins, H. Bluethmann, JG Richards,
Proc ISMRM 10, 1208 (2002).

Proton spectroscopy of white matter in the healthy elderly: Relationships with age, working memory, and APOE status.
RA Yeo, I Driscoll, J Bish, D Weers, H Petropoulos, R Jung, S Kernan, R Baumgartner, P Garry, WB Brooks,
Proc ISMRM 10, 1317 (2002).

Detection of elevated levels of glutathione in meningiomas by quantitative in vivo ¹H MRS.
KS Opstad, SW Provencher, BA Bell, JR Griffiths , FA Howe,
Proc ISMRM 10, 2035 (2002).

Characterization of an intracranial neoplasm of lipoid origin by ¹H MR spectroscopy.
M Rijpkema, Y van der Meulen, J Schuuring, E Mooyaart, M van der Graaf, A Heerschap,
Proc ISMRM 10, 2042 (2002).

In vivo localized ¹H-MR spectroscopy on the effects of radiation damage in the rat cervical spinal cord.
JA Pikkemaat, HP Bijl, MEP Philippens, DWJ Klomp, JJA van Asten, AJ van der Kogel, A Heerschap,
Proc ISMRM 10, 2148 (2002).

Reproducibility of absolute metabolite concentration evaluated by intraclass correlation coefficient using clinical MR apparatus.
H Kubo, M Harada, M Sakama, H Nishitani,
Proc ISMRM 10, 2515 (2002).

Effects of physiologic human brain motion on proton spectroscopy: Quantitative analysis and correction by cardiac gating.
PM Pattany, BC Bowen, IH Khamis, K Goodkin, RG Weaver, JB Murdoch, RM Quencer,
Proc ISMRM 10, 2518 (2002).

MRS of pediatric bipolar and disruptive behavior disorders.
P Davanzo, S Barnett, TN Venkatraman, K Yue, M Frye, N Binesh, A Huda, MA Thomas,
Proc ISMRM 10, 2553 (2002).

Automatic quantitation of localized in vivo ¹H spectra with LCModel.
SW Provencher,
NMR Biomed 14, 260-264 (2001).

Subtle prefrontal neuropathology in a pilot magnetic resonance spectroscopy study in patients with borderline personality disorder.
L Tebartz van Elst, T Thiel, B Hesslinger, K Lieb, M Bohus, J Hennig, D Ebert,
J Neuropsychiatry Clin Neurosci 13, 511-514 (2001).

Altered white and gray matter metabolism in CADASIL. A proton MR spectroscopy and ¹H-MRSI study.
DP Auer et al, Neurology 56, 635-642 (2001).

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine.
B Czéh et al, Proc Natl Acad Sci USA 98, 12796-12801 (2001).

Attention-deficit disorder in adults with or without hyperactivity: where is the difference? A study in humans using short echo ¹H-magnetic resonance spectroscopy.
B Hesslinger et al, Neurosci Lett 304, 117-119 (2001).

In Vivo short echo time ¹H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes.
MA McLean et al, Neuroimage 14, 501-509 (2001).

Absence of N-acetylaspartate in the human brain: Impact on neurospectroscopy?
E Martin et al, Ann Neurol 49, 518-521 (2001).

et al

Ann Neurol

50

Gender-specific alterations of cerebral metabolite with aging and cortisol treatment.
T Michaelis et al, J Psychiatric Res , 231-237 (2001).

Volume correction for edema in single-volume proton MR spectroscopy of contrast-enhancing multiple sclerosis lesions.
G Helms, Magn Reson Med 46, 256-263 (2001).

Reduced NAA in the thalamus and altered membrane and glial metabolism in schizophrenic patients detected by ¹H-MRS and tissue segmentation.
DP Auer et al, Schizophr Res 52, 87-99 (2001).

Chemical pathology in brain white matter of recently detoxified alcoholics: A ¹H magnetic resonance spectroscopy investigation of alcohol-associated frontal lobe injury.
BC Schweinsburg et al, Alcohol Clin Exp Res 25, 924-934 (2001).

Case study: Caudate glutamatergic changes with paroxetine persist after medication discontinuation in pediatric OCD.
J Bolton et al, J Am Acad Child Adolesc Psychiatry 40, 903-906 (2001).

Metabolic changes in quinolinic acid-lesioned rat striatum detected non-invasively by in vivo ¹H NMR spectroscopy.
I Tkac et al, J Neurosci Res 66, 891-898 (2001).

Preliminary evidence for neuronal damage in cortical grey matter and normal appearing white matter in short duration relapsing-remitting multiple sclerosis: a quantitative MR spectroscopic imaging study.
P Kapeller et al, J Neurol 248, 131-138 (2001).

Correlation of the apparent diffusion coefficient and the creatine level in early ischemic stroke: A comparison of different patterns by magnetic resonance.
H Rumpel et al, J Magn Reson Imaging 13, 335-343 (2001).

Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
FG Woermann et al, Brain 124, 427-436 (2001).

Temporal lobe changes following radiation therapy: imaging and proton MR spectroscopic findings.
VFH Chong et al, Eur Radiol 11, 317-324 (2001).

Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy.
T Kuhlmann et al, J Neurol Neurosurg Psychiatry 70, 259-262 (2001).

Homozygosity (E140K) in SCO2 causes delayed infantile onset of cardiomyopathy and neuropathy.
M Jaksch et al, Neurology 57, 1440-1446 (2001).

MR in phenylketonuria-related brain lesions.
M Dezortová et al, Acta Radiologica 42, 459-466 (2001).

Restoration of motion-related signal loss and line-shape deterioration of proton MR spectra using the residual water as intrinsic reference.
G Helms et al, Magn Reson Med 46, 395-400 (2001).

Improved analysis of ¹H-MR spectra in the presence of mobile lipids.
DP Auer et al, Magn Reson Med 46, 615-618 (2001).

Differentiation of glucose transport in human brain gray and white matter.
RA de Graaf et al, J Cereb Blood Flow Metab 21, 483-492 (2001).

Clinical and biochemical effects of zileuton in patients with Sjögren-Larsson syndrome.
MAAP Willemsen et al, Eur J Pediatr 160, 711-717 (2001).

Magnetic resonance markers of ischaemia: their correlation with vasodilatory reserve in patients with carotid artery stenosis and occlusion.
D Lythgoe et al, J Neurol Neurosurg Psychiatry 71, 58-62 (2001).

In vivo and in vitro NMR spectroscopy reveal a putative novel inborn error involving polyol metabolism.
SH Moolenaar et al, NMR Biomed 14, 167-176 (2001).

Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis.
I Mader et al, Brain 124, 953-961 (2001).

Magnetization transfer of water T₂ relaxation components in human brain: implications for T₂-based segmentation of spectroscopic volumes.
G Helms et al, Magn Reson Imaging 19, 803-811 (2001).

Volume-selective proton MR spectroscopy for in vitro quantification of anticonvulsants.
J Braun et al, Neuroradiology 43, 211-217 (2001).

Metabolic information from the human fetal brain obtained with proton magnetic resonance spectroscopy.
RD Kok et al, Am J Obstet Gynecol 185, 1011-1015 (2001).

Quantification of ¹H NMR spectra of the human brain using LCModel and spin simulations at 7 Tesla.
I Tkac et al, Proc ISMRM, 214 (2001).

Evidence of subtle prefrontal neuropathology in patients with borderline personality disorder. A pilot proton magnetic resonance spectroscopy study.
T Thiel et al, Proc ISMRM, 381 (2001).

Is voxel composition and NAA as measured by ¹H MRS influenced by structural abnormalities associated with major depressive disorder?
B Pfleiderer et al, Proc ISMRM, 382 (2001).

A short echo time proton magnetic resonance spectroscopic imaging study of metabolites in temporal lobe epilepsy.
RJ Simister et al, Proc ISMRM, 387 (2001).

Using ¹H-MR spectroscopy in forensic medicine to estimate the post-mortem interval: A pilot study in an animal model and its application to human brain.
M Ith et al, Proc ISMRM, 388 (2001).

Absolute quantification of metabolites in white matter using MR spectroscopy in patients with MS or syndromes suggestive of MS with normal MRI scans of the brain.
M Gustafsson et al, Proc ISMRM, 467 (2001).

Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute MS.
I Mader et al, Proc ISMRM, 468 (2001).

T₂-based volume correction for edema in single volume MRS of contrast-enhancing multiple sclerosis lesions.
G Helms, Proc ISMRM, 469 (2001).

In vivo quantification of metabolites in the hippocampus, striatum, and cortex of the developing neonatal rat.
I Tkac et al, Proc ISMRM, 488 (2001).

Electroconvulsive therapy induces metabolic changes in severe depressed patients in the anterior cingulum.
B Pfleiderer et al, Proc ISMRM, 558 (2001).

Brain neurochemical abnormalities in childhood autism.
SD Friedman et al, Proc ISMRM, 577 (2001).

Quantitative analysis of brain metabolites in 13 patients with Sjögren-Larsson syndrome.
M van der Graaf et al, Proc ISMRM, 583 (2001).

In vivo GABA measurement using a PRESS-localized double quantum filter in patients with malformations of cortical development and epilepsy.
M McLean et al, Proc ISMRM, 962 (2001).

Metabolite T₁ in multiple sclerosis lesions differs from normal.
E Brief et al, Proc ISMRM, 983 (2001).

Neurochemical correlates of late-life major depression.
A Kumar et al, Proc ISMRM, 1013 (2001).

Metabolic changes in the brain of depressive patients.
S Gruber et al, Proc ISMRM, 1021 (2001).

Brain and immune changes in response to psychosocial stress are reversed by tianeptine.
T Michaelis et al, Proc ISMRM, 1028 (2001).

LC-Model analysis of anterior cingulate ¹H MRS in juvenile bipolar disorder.
PA Davanzo et al, Proc ISMRM, 1356 (2001).

Parameterized evaluation of pathological macromolecules in proton MR spectra of the human brain.
U Seeger et al, Proc ISMRM, 1659 (2001).

Metabolite quantitation reproducibility in serial ¹H-MRSI studies of human brain using a stereotactic immobilization/repositioning frame.
AZ Damyanovich et al, Proc ISMRM, 1681 (2001).

In vivo metabolite T₂ accurately measured with large TE range.
E Brief et al, Proc ISMRM, 1684 (2001).

Improved analysis of ¹H-MR spectra in the presence of mobile lipids: Impact on grading of malignant gliomas.
DP Auer et al, Proc ISMRM, 2283 (2001).

Characterization of oligodendrogliomas using short echo time 2D ¹H MRSI.
M Rijpkema et al, Proc ISMRM, 2304 (2001).

Quantitative analysis of short echo time ¹H-MRSI of cerebral gray and white matter.
MA McLean et al, Magn Reson Med 44, 401-411 (2000).

Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study.
DP Auer et al, Biol Psychiatry 47, 305-313 (2000).

Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: Absolute metabolic values over 2 years during a clinical pharmacological study.
I Mader et al, Am J Neuroradiol 21, 1220-1227 (2000).

MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy.
I Savic et al, Epilepsia 41, 290-296 (2000).

In vivo ¹H-magnetic resonance spectroscopy of the spinal cord in humans.
B Gómez-Ansón et al, Neuroradiology 42, 515-517 (2000).

N-Acetylaspartate concentration in the anterior cingulate of maltreated children and adolescents with PTSD.
MD De Bellis et al, Am J Psychiatry 157, 1175-1177 (2000).

Mental retardation and behavioral problems as presenting signs of a creatine synthesis defect.
MS van der Knaap et al, Ann Neurol 47, 540-543 (2000).

Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
B Wilken et al, Pediatr Neurol 23, 22-31 (2000).

A ¹H magnetic resonance spectroscopy study of aging in parietal white matter: Implications for trials in multiple sclerosis.
SM Leary et al, Magn Reson Imaging 18, 455-459 (2000).

Extracellular-Intracellular distribution of glucose and lactate in the rat brain assessed noninvasively by diffusion-weighted ¹H nuclear magnetic resonance spectroscopy in vivo.
J Pfeuffer et al, J Cereb Blood Flow Metab 20, 736-746 (2000).

MR imaging and localized proton spectroscopy of the precentral gyrus in amyotrophic lateral sclerosis.
BC Bowen et al, Am J Neuroradiol 21, 647-658 (2000).

Lesion heterogeneity in multiple sclerosis: A study of the relations between appearances on T1 weighted images, T1 relaxation times, and metabolite concentrations.
PA Brex et al, J Neurol Neurosurg Psychiatry 68, 627-632 (2000).

Detection of dimethyl sulfone in the human brain by in vivo proton magnetic resonance spectroscopy.
SE Rose et al, Magn Reson Imaging 18, 95-98 (2000).

Regression analysis of metabolite concentrations estimated from localized proton MR spectra of active and chronic multiple sclerosis lesions.
G Helms et al, Magn Reson Med 43, 102-110 (2000).

On the reliability of quantitative clinical magnetic resonance spectroscopy of the human brain.
T Schirmer et al, NMR Biomed 13, 28-36 (2000).

A precise and user-independent quantification technique for regional comparison of single volume proton MR spectroscopy of the human brain.
G Helms, NMR Biomed 13, 398-406 (2000).

Single voxel proton MR spectroscopy methods and applications in neuropediatrics.
J Frahm et al, Riv Neuroradiol 13, 7-15 (2000).

Metabolic changes in brain white matter after perinatal white matter injury.
PS Hüppi et al, Pediatr Res 47, 459A (2000).

Leukoencephalopathy associated with a disturbance in the metabolism of polyols.
MS van der Knaap et al, Ann Neurol 46, 925-928 (1999).

Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS.
E Wilichowski et al, Neuropediatrics 30, 256-263 (1999).

¹H Magnetic resonance spectroscopy of normal appearing white matter in primary progressive multiple sclerosis.
SM Leary et al, J Neurol 246, 1023-1026 (1999).

Inflammatory CNS demyelination: Histopathologic correlation with in vivo quantitative proton MR spectroscopy.
A Bitsch et al, Am J Neuroradiol 20, 1619-1627 (1999).

Magnetization transfer attenuation of creatine resonances in localized proton MRS of human brain in vivo.
G Helms et al, NMR Biomed 12, 490-494 (1999).

Brains of creatine kinase deficient mice lack phosphocreatine and exhibit an increased NAA level.
HJA in 't Zandt et al, Proc Intl Soc Magn Reson Med 8, 174 (2000).

Absolute quantitative localized ¹H MR spectroscopy and MRI on the in vivo mouse brain: Effect of genetic background.
HJA in 't Zandt et al, Proc Intl Soc Magn Reson Med 8, 180 (2000).

Quantitation of standard and less prominent metabolites in neonatal brain using short TE ¹H-MR spectroscopy and advanced model fitting.
R Kreis et al, Proc Intl Soc Magn Reson Med 8, 587 (2000).

Quantitative ¹H-MRS in early human brain development and metabolic changes after perinatal brain injury.
PS Hüppi et al, Proc Intl Soc Magn Reson Med 8, 590 (2000).

Neuronal dysfunction in the cerebral cortex of the multiple sclerosis brain demonstrated with quantitative magnetic resonance spectroscopy imaging.
P Kapeller et al, Proc Intl Soc Magn Reson Med 8, 628 (2000).

Quantitative analysis of human and macaque brain metabolites using 3 Tesla system.
N Hattori et al, Proc Intl Soc Magn Reson Med 8, 1067 (2000).

Oral cortisol and psychosocial stress differently alter brain metabolism in tree shrews.
T Michaelis et al, Proc Intl Soc Magn Reson Med 8, 1081 (2000).

Decreased cerebral N-acetylaspartate correlates with reduced brain water apparent diffusion coefficient during delayed energy failure in the newborn piglet.
JS Thornton et al, Proc Intl Soc Magn Reson Med 8, 1091 (2000).

Metabolite content in cerebral grey and white matter studied with short-echo time ¹H-MRSI.
MA McLean et al, Proc Intl Soc Magn Reson Med 8, 1131 (2000).

¹H MRS, MRI and neuropsychological testing of patients with traumatic brain injury at long elapsed time since injury.
E Brief et al, Proc Intl Soc Magn Reson Med 8, 1138 (2000).

Changes in the ¹H MR spectra of epileptogenic lesions treated with the Leksell Gamma Knife (LGK). Results from a three year period.
M Hájek et al, Proc Intl Soc Magn Reson Med 8, 1141 (2000).

In vivo drug monitoring of anticonvulsants in the human brain using proton MRS.
J Braun et al, Proc Intl Soc Magn Reson Med 8, 1148 (2000).

Complete absence of creatine in the adult brain.
T Thiel et al, Proc Intl Soc Magn Reson Med 8, 1175 (2000).

N-Acetyl-Aspartate: A marker for viable neurons?
T Thiel et al, Proc Intl Soc Magn Reson Med 8, 1909 (2000).

Differential diagnosis of focal brain lesions in children by quantitative single-voxel proton magnetic resonance spectroscopy.
P Dechent et al, Proc Intl Soc Magn Reson Med 8, 1921 (2000).

Metabolite concentrations of pons, medulla, motor cortex in normal human brain using 2D CSI.
B Yang et al, Proc Intl Soc Magn Reson Med 8, 1937 (2000).

Metabolite T₁ differs within and between regions of normal human brain.
EE Brief et al, Proc Intl Soc Magn Reson Med 8, 1939 (2000).

Coherent averaging of proton MR spectroscopy data using the residual water resonance as intrinsic reference.
G Helms et al, Proc Intl Soc Magn Reson Med 8, 1948 (2000).

Inter- and intra-site reproducibility of in vivo metabolite quantification with proton magnetic resonance spectroscopic imaging.
DT Chard et al, Proc Intl Soc Magn Reson Med 8, 1963 (2000).

Towards an in vivo neurochemical profile: Quantification of 18 metabolites in short-echo-time ¹H NMR spectra of the rat brain.
J Pfeuffer et al, J Magn Reson 141, 104 (1999).

Proton MR spectroscopy in clinically isolated syndromes suggestive of multiple sclerosis.
PA Brex et al, J Neurol Sci 166, 16 (1999).

Analysis of 1.5 Tesla proton MR spectra of human brain using LCModel and an imported basis set.
G Helms, Magn Reson Imaging 17, 1211 (1999).

Short echo time single-voxel ¹H magnetic resonance spectroscopy in magnetic resonance imaging-negative temporal lobe epilepsy: Different biochemical profile compared with hippocampal sclerosis.
FG Woermann et al, Ann Neurol 45, 369 (1999).

¹H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla.
EP Pioro et al, Neurology 53, 71 (1999).

Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy.
MAA van Walderveen et al, Ann Neurol 46, 79 (1999).

Neither short-term nor long-term administration of oral choline alters metabolite concentrations in human brain.
P Dechent et al, Biol Psychiatry 46, 406 (1999).

Localized Proton MRS of the human hippocampus: Metabolite concentrations and relaxation times.
CG Choi et al, Magn Reson Med 41, 204 (1999).

Magnetic resonance proton spectroscopy of the brain in Wilson's disease.
E Kraft et al, J Neurol 246, 693 (1999).

Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS.
PJW Pouwels et al, Pediatr Res 46, 474 (1999).

A ¹H MRS study of probable Alzheimer's disease and normal aging: Implications for longitudinal monitoring of dementia progression.
SE Rose et al, Magn Reson Imaging 17, 291 (1999).

Increase of total creatine in human brain after oral supplementation of creatine-monohydrate.
P Dechent et al, Am J Physiol 277, R698 (1999).

Multimodal MR Imaging: Functional, diffusion tensor, and chemical shift imaging in a patient with localization-related epilepsy.
K Krakow et al, Epilepsia 40, 1459 (1999).

Proton MRS of oral creatine supplementation in rats. Cerebral metabolite concentrations and ischemic challenge.
T Michaelis et al, NMR Biomed 12, 309 (1999).

Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: ¹H MR spectroscopic findings.
VFH Chong et al, Int J Radiation Oncology Biol Phys 45, 699 (1999).

Proton MR spectroscopy in a child with pyruvate dehydrogenase complex deficiency.
ME Rubio-Gozalbo et al, Magn Reson Imaging 17, 939 (1999).

Quantitative Proton MRS of cerebral multiple sclerosis lesions: Regression analysis of metabolite concentrations.
G Helms et al, Proc Intl Soc Magn Reson Med 7, 43 (1999).

Correlation of ADC values with creatine levels in acute ischemic stroke.
H Rumpel et al, Proc Intl Soc Magn Reson Med 7, 226 (1999).

In vivo ¹H NMR spectroscopy of the developing rat hippocampus.
I Tkac et al, Proc Intl Soc Magn Reson Med 7, 338 (1999).

Diffusion-weighted¹H NMR spectroscopy of glucose in rat brain in vivo at very large b values.
J Pfeuffer et al, Proc Intl Soc Magn Reson Med 7, 564 (1999).

Normalization of quantitative metabolite maps.
MA McLean et al, Proc Intl Soc Magn Reson Med 7, 585 (1999).

Model fitting of ¹H-MR spectra of the human brain: Incorporation of short-T₁ components and evaluation of parameterized vs. non-parameterized models.
L Hofmann et al, Proc Intl Soc Magn Reson Med 7, 586 (1999).

Metabolic changes in quinolinic acid-lesioned rat striatum studied by in vivo ¹H NMR spectroscopy.
I Tkac et al, Proc Intl Soc Magn Reson Med 7, 731 (1999).

Detection and assignment of phosphocreatine signal in vivo in ¹H NMR spectra at 9.4 Tesla.
J Pfeuffer et al, Proc Intl Soc Magn Reson Med 7, 1363 (1999).

Reduced frontal lobe N-acetyl aspartate in patients with juvenile myoclonic epilepsy as detected by localized MRS in vivo.
I Savic et al, Proc Intl Soc Magn Reson Med 7, 1428 (1999).

Differences of metabolites in mesial and lateral temporal lobes.
Y Wang et al, Proc Intl Soc Magn Reson Med 7, 1429 (1999).

Influence of partial volume effect on metabolite concentrations in multiple sclerosis lesions estimated from localized proton MR spectra.
L Stawiarz et al, Proc Intl Soc Magn Reson Med 7, 1439 (1999).

T₂ measurement, magnetization transfer and segmentation of extra- and intracellular volumes on discrete "black hole" multiple sclerosis lesions.
G Helms et al, Proc Intl Soc Magn Reson Med 7, 1442 (1999).

Brain proton magnetic resonance spectroscopy of patients with the Sjögren-Larsson syndrome.
A Heerschap et al, Proc Intl Soc Magn Reson Med 7, 1447 (1999).

An MR study of lesion heterogeneity in patients with secondary progressive MS: Correlation between metabolic concentration, T1 relaxation time and appearance on T1-weighted MRI.
PA Brex et al, Proc Intl Soc Magn Reson Med 7, 1451 (1999).

The contribution of magnetic resonance to explaining phenylketonuria brain lesions.
M Dezortová et al, Proc Intl Soc Magn Reson Med 7, 1456 (1999).

Metabolic asymmetries as an early indicator for temporal lobe epilepsy in children. A comparison with EEG and high resolution MRI.
T Thiel et al, Proc Intl Soc Magn Reson Med 7, 1473 (1999).

Brain metabolite alterations after oral cortisol: A proton MRS study of tree shrews.
T Michaelis et al, Proc Intl Soc Magn Reson Med 7, 1478 (1999).

Metabolite T₁ relaxation differs between and within regions of normal human brain.
E Brief et al, Proc Intl Soc Magn Reson Med 7, 1555 (1999).

Precision of MRS metabolite peak area ratios in human brain at short TE.
E Brief et al, Proc Intl Soc Magn Reson Med 7, 1556 (1999).

Interactive ROI analysis in ¹H-CSI.
MA McLean et al, Proc Intl Soc Magn Reson Med 7, 1562 (1999).

Application of LCModel for quality control and quantitative in vivo ¹H MR spectroscopy by short echo time STEAM sequence.
M Hájek et al, Proc Intl Soc Magn Reson Med 7, 1575 (1999).

Quantitative proton magnetic resonance spectroscopy of childhood adrenoleukodystrophy.
PJW Pouwels et al, Neuropediatrics 29, 254 (1998).

Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS.
PJW Pouwels et al, Magn Reson Med 39, 53 (1998).

Proton T₂ relaxation of cerebral metabolites during transient global ischemia in rat brain.
H Fujimori et al, Magn Reson Med 39, 647 (1998).

Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome.
B Kruse et al, Pediatr Neurol 18, 176 (1998).

MR spectroscopy in amyotrophic lateral sclerosis / motor neuron disease.
EP Pioro, J Neurol Sci 152 (Suppl 1), S49 (1997).

Stability measure of ¹H MRS in normal older adults: Implications for longitudinal monitoring of Alzheimer's disease.
SE Rose et al, Proc ISMRM, 426 (1998).

Automated production of quantitative metabolite maps from short echo time ¹H-CSI of the brain.
MA McLean et al, Proc ISMRM, 626 (1998).

Does cerebral proton MR spectroscopy reflect tissue alterations and/or clinical impairment in HIV-related encephalitis (progressive diffuse leukencephalopathy)?
G-K Elbel et al, Proc ISMRM, 1709 (1998).

Tailored single voxel short TE MR spectroscopy in temporal lobe epilepsy - Absolute quantitation with partial volume correction for cerebrospinal fluid.
FG Woermann et al, Proc ISMRM, 1726 (1998).

Oral creatine and cerebral metabolism. Metabolite concentrations and ischemic challenge in rat brain.
T Michaelis et al, Proc ISMRM, 1764 (1998).

Automated prior knowledge fitting of over-sampled J-resolved spectra.
N Sailasuta et al, Proc ISMRM, 1842 (1998).

In vivo ¹H magnetic resonance spectroscopy of the spinal cord in humans.
B Gomez-Anson et al, Proc ISMRM, 1887 (1998).

Correction of in vivo spectra for individual CSF content in the human brain.
T Schirmer et al, Proc ISMRM, 1900 (1998).

MR diffusion and proton spectroscopy in cerebral gliomas.
DP Auer et al, MAGMA (Suppl 1), 8 (1998).

Diffusion-weighted in vivo ¹H NMR spectroscopy of brain glucose and metabolites.
J Pfeuffer et al, MAGMA (Suppl 1), 9 (1998).

Towards an in vivo neurochemical profile: Quantitation of metabolites in ultra-short echo time ¹H MRS of rat brain accounting for macromolecule resonances.
J Pfeuffer et al, MAGMA (Suppl 1), 15 (1998).

Evaluation of metabolite quantitation reliability in ¹H 2D-CSI spectroscopy data using a fully automated analysis routine.
AZ Damyanovich et al, MAGMA (Suppl 1), 74 (1998).

Automation of quality control procedures for in vivo MR spectroscopy.
M Burian et al, MAGMA (Suppl 1), 152 (1998).

Cerebral metabolic changes observed in immunoglobulin treatment of a case of Balo's concentric sclerosis. A proton magnetic resonance spectroscopy (¹H MRS) study.
NR Bolo et al, MAGMA (Suppl 1), 227 (1998).

Analysis of proton brain spectra from human infants by fitting linear combinations of model spectra.
EB Cady et al, J Magn Reson Anal 3, 5 (1997).

Improved sensitivity to overlapping multiplet signals in in vivo proton spectroscopy using a multiecho volume selective (CPRESS) experiment.
J Hennig et al, Magn Reson Med 37, 816 (1997).

Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS.
PJW Pouwels et al, NMR Biomed 10, 73 (1997).

Localized proton magnetic resonance spectroscopy of brain disorders in childhood.
J Frahm et al, Advances in Neurochemistry 8, 329 (1997).

¹H-magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum.
D Ebert et al, Psychiatry Res 74, 173 (1997).

Grading and therapy monitoring of astrocytomas with ¹H spectroscopy.
W Bini et al, Neurocirugia 8, 171 (1997).

Alterations in brain metabolism after high-dose glucocorticoid therapy: a proton magnetic resonance spectroscopy study.
D Auer et al, Proc ISMRM, 407 (1997).

Age dependence of human cerebral metabolites in gray matter, white matter, and basal ganglia as determined by quantitative localized proton MRS.
PJW Pouwels et al, Proc ISMRM, 482 (1997).

Proton magnetic resonance spectroscopy in amyotrophic lateral sclerosis.
D Auer et al, Proc ISMRM, 1186 (1997).

Characteristics of metabolites in multiple sclerosis (MS) plaques by quantitative proton MRS.
L Stawiarz et al, Proc ISMRM, 1192 (1997).

Cerebral drug effects investigated by ¹HMR-spectroscopy in volunteers and patients.
T Burau et al, Proc ISMRM, 1244 (1997).

Local sensitivity corrrection in quantitative localized proton MRS of the human brain.
G Helms, Proc ISMRM, 1404 (1997).

Automated quantitation of localized ¹H MR spectra in vivo at short echo times with baseline distortion.
SW Provencher, Proc ISMRM, 1411 (1997).

Localized proton magnetic resonance spectroscopy of cerebral metabolic disturbances in children with neuronal ceroid lipofuscinosis.
K Brockmann et al, Neuropediatrics 27, 242 (1996).

Localized proton magnetic resonance spectroscopy of a cerebellar tumor in a two-year-old child.
B Wilken et al, Child's Nerv Syst 12, 626 (1996).

Creatine replacement therapy in guanidinoacetate methyltransferace deficiency, a novel inborn error of metabolism.
S Stöckler et al, Lancet 348, 789 (1996).

Grading and therapy monitoring of astrocytomas with ¹H-spectroscopy: Preliminary study.
O Speck et al, Anticancer Res 16, 1581 (1996).

Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man.
J Frahm et al, Magn Reson Med 35, 143 (1996).

Arrested cerebral adrenoleukodystrophy: A clinical and proton magnetic resonance study in three patients.
GC Korenke et al, Pediatr Neurol 15, 103 (1996).

Localized proton magnetic resonance spectroscopy of cerebral metabolites.
J Frahm et al, Neuropediatrics 27, 64 (1996).

¹H spectroscopy in obsessive compulsive disorder: Evidence for neuronal loss in the cingulate gyrus and the striatum.
O Speck et al, Proc ISMRM, 997 (1996).

Comparison of short TE single voxel spectroscopic methods using prior knowledge fitting.
N Sailasuta et al, Proc ISMRM, 1187 (1996).

Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS.
P Pouwels et al, Proc ESMRMB, 77 (1996).

Long-term follow up with MRI and proton spectroscopy in Wilson's disease.
E Kraft et al, Proc ESMRMB, 140 (1996).

Localized in vivo proton spectroscopy (PRESS) at short echo times between 8 and 30 ms.
T Thiel et al, Proc ESMRMB, 228 (1996).

Hemimegalencephaly: Localized proton magnetic resonance spectroscopy in vivo.
F Hanefeld et al, Epilepsia 36, 1215 (1995).

Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion.
M Wick et al, Stroke 26, 1930 (1995).

Localized proton magnetic resonance spectroscopy of cerebral abnormalities in children with carbohydrate-deficient glycoprotein syndrome.
U Holzbach et al, Acta Paediatr 84, 781 (1995).

Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo.
Y Nagatomo et al, NMR Biomed 8, 265 (1995).

Cerebral proton magnetic resonance spectroscopy in Rett syndrome.
F Hanefeld et al, Neuropediatrics 26, 126 (1995).

¹H MRS in valproate-induced hyperammonemia with encephalopathy.
S Ziyeh et al, Proc SMR, 1836 (1995).

Automated quantitation of localized ¹H MR spectra in vivo: Capabilities and limitations.
SW Provencher et al, Proc SMR, 1952 (1995).

Improvements in the evaluation of in vivo proton MR spectra using a fully automated data analysis method (LCModel).
W Hänicke et al, Proc SMR, 1953 (1995).

On the concentration gradient of cerebral metabolites in human gray matter as determined by quantitative localized proton MRS.
PJW Pouwels et al, Proc SMR, 1957 (1995).

Creatine deficiency in the brain: A new, treatable inborn error of metabolism.
S Stöckler et al, Pediatr Res 36, 409 (1994).

In Vivo proton magnetic resonance spectroscopy of the brain in a patient with L-2-hydroxyglutaricacid acidemia.
F Hanefeld et al, Pediatr Res 35, 614 (1994).

Monitoring of cerebral metabolites during forebrain ischemia in rat in vivo by localized proton MRS.
F Prielmeier et al, Proc SMR, 1407 (1994).

Alterations of brain metabolites in metachromic leukodystrophy as detected by localized proton magnetic resonance spectroscopy in vivo.
B Kruse et al, J Neurol 241, 68 (1993).

Quantitative proton MRS in vivo shows cerebral myo-inositol and cholines to be unchanged in manic-depressive patients treated with lithium.
H Bruhn et al, Proc SMR, 977 (1993).

On the use of a fully automated data analysis method for in vivo MRS. Metabolite concentrations and relaxation times from proton spectra of human brain.
W Hänicke et al, Proc SMR, 1543 (1993).

Contact: Stephen Provencher: sp@lcmodel.CA

Last modified: 13 November 2026